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Clinical and genetic profiles of the 369 patients enrolled in the JPLSG AML...
Published: 2019
Figure 1. Clinical and genetic profiles of the 369 patients enrolled in the JPLSG AML-05 trial. (A) Pie chart represented the frequency of each gene alterations. (B) Landscape of 369 de novo pediatric AML patients. Each column indicates 1 patient. * ,# Both gene fusions were observed in the same... More
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Novel/rare fusion genes identified in patients with de novo pediatric AML. ...
Published: 2019
Figure 2. Novel/rare fusion genes identified in patients with de novo pediatric AML. (A-D) The structure of the detected fusion proteins. (A) Five RUNX1 rearrangements. (B) Three ETV6 rearrangements. (C) Three NPM1 rearrangements. (D) Other novel gene fusions. R1, R2, and R3 are 51 ± 52 am... More
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Unsupervised hierarchical clustering analysis of the 139 patients with pedi...
Published: 2019
Figure 3. Unsupervised hierarchical clustering analysis of the 139 patients with pediatric AML. (A) Two-dimensional hierarchical clustering analysis of the 139 patients was performed using 3106 probe sets that were differentially expressed in 139 patients. (B) We showed the detail of gene expres... More
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Unsupervised hierarchical clustering analysis of the 139 patients with pedi...
Published: 2019
Figure 3. Unsupervised hierarchical clustering analysis of the 139 patients with pediatric AML. (A) Two-dimensional hierarchical clustering analysis of the 139 patients was performed using 3106 probe sets that were differentially expressed in 139 patients. (B) We showed the detail of gene expres... More
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Correlations between established risk factors for pediatric AML.  The diagr...
Published: 2019
Figure 4. Correlations between established risk factors for pediatric AML. The diagram indicates co-occurrence or mutual exclusivity between pairs of clinical features, genetic alterations, gene expressions, and outcomes. The circles indicate that crossed factors are statistically co-occurrent (... More
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Study overview.  (A) Study design. (B) Frequency of study patients by their...
Published: 2019
Figure 1. Study overview. (A) Study design. (B) Frequency of study patients by their HLA-DRB1 and -DQB1 alleles, with alleles ordered from most to least frequent. (C) Heat map of genetic linkage detected between HLA-DRB1 and -DQB1 alleles. Intensity (overlap) equals the number of patients having... More
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Study overview.  (A) Study design. (B) Frequency of study patients by their...
Published: 2019
Figure 1. Study overview. (A) Study design. (B) Frequency of study patients by their HLA-DRB1 and -DQB1 alleles, with alleles ordered from most to least frequent. (C) Heat map of genetic linkage detected between HLA-DRB1 and -DQB1 alleles. Intensity (overlap) equals the number of patients having... More